We are the leading supplier of Sodium Methyl Paraben E. P. Specifications: 1CharactersA white, crystalline powder, freely soluble in water, sparingly soluble in alcohol, practically insoluble in methylene chloride.2IdentificationFirst identification A, B, ESecond identification A, C, D, E A. Dissolve 0.5 g in 50 ml of water R. Immediately adds 5ml of hydrochloric acid R1. Filter and wash the precipitate with water R. Dry under vacuum at 80oC for 2 hours. The precipitate obtained melts (2.2.14) at 125 DegreeC to 128 DegreeC. B. Examine the precipitate obtained in identification test A by infrared absorption spectrophotometry (2.2.24) comparing with the spectrum obtained with methyl parahydroxy benzoate CRS. C. Examine the chromatograms obtained in the test for related substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position and size to the principal spot in the chromatogram obtained with reference solution (c). D. To about 10 mg in a test-tube add 1 ml of sodium carbonate solution R, boil for 30s and cool. Add 5 ml of aminopyrazolone solution R and 1 ml of potassium ferricyanide solution R and mix. An orange to red colour develops. E. To 1 ml of Solution S (see Tests) add 1 ml of water R. The solution gives reaction (a) of sodium (2.3.1)3Appearance of solutionDissolve 5 gm in carbon-dioxide free water R prepared from distilled water R and dilute to 50 ml examine immediately after preparation is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method I).4pHBetween 9.5 to 10.5 (1 gm in 1000 ml carbon-dioxide free water)5Related substancesImpurity A: any spot due to impurity A is not more intense than the spot in the Chromatogram obtained with reference solution (a) (4 %)Any other impurity: Any spot, apart from the principal spot and due to 4-hydroxy benzoic acid is not more intense than the spot in the chromatogram obtained with reference solution (b) (0.5 %)System suitability: The test is not valid unless the chromatogram obtained with reference solution (d) showstwoclearlyseparated principal spots.6ChloridesNot more than 350 ppm.7SulphateNot more than 300 ppm.8Heavy MetalsNot more than 10 ppm.9WaterNot more than 5.0%.10AssayNot less than 99.0% to not more than 102.0% of sodium 4(methoxycabonyl)Phenolate, calculated with reference to the anhydrous substance.
Packaging Size - 25 kg
Packaging Type - Bag
Grade Standard - Technical Grade
Usage - Industrial
Physical State - Crystals
We are the leading supplier of Sodium Methyl Paraben E. P. Specifications: 1CharactersA white, crystalline powder, freely soluble in water, sparingly soluble in alcohol, practically insoluble in methylene chloride.2IdentificationFirst identification A, B, ESecond identification A, C, D, E A. Dissolve 0.5 g in 50 ml of water R. Immediately adds 5ml of hydrochloric acid R1. Filter and wash the precipitate with water R. Dry under vacuum at 80oC for 2 hours. The precipitate obtained melts (2.2.14) at 125 DegreeC to 128 DegreeC. B. Examine the precipitate obtained in identification test A by infrared absorption spectrophotometry (2.2.24) comparing with the spectrum obtained with methyl parahydroxy benzoate CRS. C. Examine the chromatograms obtained in the test for related substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position and size to the principal spot in the chromatogram obtained with reference solution (c). D. To about 10 mg in a test-tube add 1 ml of sodium carbonate solution R, boil for 30s and cool. Add 5 ml of aminopyrazolone solution R and 1 ml of potassium ferricyanide solution R and mix. An orange to red colour develops. E. To 1 ml of Solution S (see Tests) add 1 ml of water R. The solution gives reaction (a) of sodium (2.3.1)3Appearance of solutionDissolve 5 gm in carbon-dioxide free water R prepared from distilled water R and dilute to 50 ml examine immediately after preparation is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method I).4pHBetween 9.5 to 10.5 (1 gm in 1000 ml carbon-dioxide free water)5Related substancesImpurity A: any spot due to impurity A is not more intense than the spot in the Chromatogram obtained with reference solution (a) (4 %)Any other impurity: Any spot, apart from the principal spot and due to 4-hydroxy benzoic acid is not more intense than the spot in the chromatogram obtained with reference solution (b) (0.5 %)System suitability: The test is not valid unless the chromatogram obtained with reference solution (d) showstwoclearlyseparated principal spots.6ChloridesNot more than 350 ppm.7SulphateNot more than 300 ppm.8Heavy MetalsNot more than 10 ppm.9WaterNot more than 5.0%.10AssayNot less than 99.0% to not more than 102.0% of sodium 4(methoxycabonyl)Phenolate, calculated with reference to the anhydrous substance.
Packaging Size - 25 kg
Packaging Type - Bag
Grade Standard - Technical Grade
Usage - Industrial
Physical State - Crystals